Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Simple and rapid nicotine analysis using a disposable silica nanochannel-assisted electrochemiluminescence sensor

Author affiliations

Abstract

Nicotine analysis is essential to medicine, toxicology and the tobacco industry. However, no simple, portable and disposable method was developed to meet their demands. Here, we report a simple, rapid and disposable silica nanochannel (SAN)-based electrochemiluminescence (ECL) sensor for nicotine analysis by simply assembling a SAN electrode with a paper cover. The sensing principle of the disposable sensor is based on the size exclusion effect and charge selectivity, which obviously prolong the sensor service time. We find that the sensor exhibits good specificity to nicotine, and most of the complex matrices are unlikely to impact the detection. The performance of the disposable sensor in cigarettes, e-cigarettes, nicotine gums, and lozenges is fully validated, showing satisfactory linearity, sensitivity (a limit of detection of 27.82 nM), and accuracy (a recovery between 96.00% and 106.51%). The disposable sensor can be potentially applied for on-site nicotine analysis.

Graphical abstract: Simple and rapid nicotine analysis using a disposable silica nanochannel-assisted electrochemiluminescence sensor

Back to tab navigation

Supplementary files

Article information


Submitted
25 Mar 2020
Accepted
09 Jun 2020
First published
09 Jun 2020

Analyst, 2020, Advance Article
Article type
Paper

Simple and rapid nicotine analysis using a disposable silica nanochannel-assisted electrochemiluminescence sensor

Y. Xiao, S. Chen, G. Zhang, Z. Li, H. Xiao, C. Chen, C. He, R. Zhang and X. Yang, Analyst, 2020, Advance Article , DOI: 10.1039/D0AN00588F

Social activity

Search articles by author

Spotlight

Advertisements