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Issue 10, 2020
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Development of a lateral flow test for rapid pyrethroid detection using antibody-gated indicator-releasing hybrid materials

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Abstract

The employment of type-I pyrethroids for airplane disinfection in recent years underlines the necessity to develop sensing schemes for the rapid detection of these pesticides directly at the point-of-use. Antibody-gated indicator-releasing materials were thus developed and implemented with test strips for lateral-flow assay-based analysis employing a smartphone for readout. Besides a proper matching of pore sizes and gating macromolecules, the functionalization of both the material's outer surface as well as the strips with PEG chains enhanced system performance. This simple assay allowed for the detection of permethrin as a target molecule at concentrations down to the lower ppb level in less than 5 minutes.

Graphical abstract: Development of a lateral flow test for rapid pyrethroid detection using antibody-gated indicator-releasing hybrid materials

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Article information


Submitted
13 Feb 2020
Accepted
04 Apr 2020
First published
06 Apr 2020

Analyst, 2020,145, 3490-3494
Article type
Communication

Development of a lateral flow test for rapid pyrethroid detection using antibody-gated indicator-releasing hybrid materials

E. Costa, E. Climent, S. Ast, M. G. Weller, J. Canning and K. Rurack, Analyst, 2020, 145, 3490
DOI: 10.1039/D0AN00319K

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