Jump to main content
Jump to site search

Issue 7, 2020
Previous Article Next Article

Intact NMR spectroscopy: slow high-resolution magic angle spinning chemical shift imaging

Author affiliations

Abstract

High-Resolution Magic-Angle Spinning Chemical Shift Imaging (HR-MAS CSI) has recently been explored for nuclear magnetic resonance (NMR) metabolomics and shows considerable promise in organism research. This is due to its ability to offer a supplemental dimension – spatial metabolic distribution – for profiling. However, HR-MAS CSI suffers from the large centrifugal stress exerted on the sample, which inevitably hinders the metabolic assessment. Herein, a slow sample spinning strategy was implemented and evaluated. The results demonstrate its potential as a highly informative profiling approach for intact specimens, with high quality data and feasibility.

Graphical abstract: Intact NMR spectroscopy: slow high-resolution magic angle spinning chemical shift imaging

Back to tab navigation

Supplementary files

Article information


Submitted
16 Jan 2020
Accepted
26 Feb 2020
First published
04 Mar 2020

Analyst, 2020,145, 2520-2524
Article type
Communication

Intact NMR spectroscopy: slow high-resolution magic angle spinning chemical shift imaging

C. Lucas-Torres and A. Wong, Analyst, 2020, 145, 2520
DOI: 10.1039/D0AN00118J

Social activity

Search articles by author

Spotlight

Advertisements