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Colorimetric detection of Hg(ii) based on the gold amalgam-triggered reductase mimetic activity in aqueous solution by employing AuNP@MOF nanoparticles

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Abstract

Although the potential of gold amalgam as a nanoenzyme has been demonstrated, its practical utility has been limited by its low catalytic activity caused by the aggregation of Au nanoparticles (Au NPs). Thus, there is a need to further engineer Au NPs to prevent aggregation and then to achieve higher enzyme activities for the detection of Hg2+ ions. Metal organic frameworks (MOFs), as one kind of promising material, have attracted particular attention due to their unique characteristics of uniform cavities and very high porosity. Herein, a hybrid material of Au nanoparticles and a MOF (AuNP@MOF), constructed by immobilization of Au NPs uniformly on the cavity surface of an iron-5,10,15,20-tetrakis (4-carboxyl)-21H,23H-porphyrin-based MOF (Fe-TCPP-MOF), has been successfully synthesized. Based on Hg2+ ion triggered Au catalysis of methylene blue (MB) reduction, a colorimetric method for highly sensitive and selective detection of Hg2+ ions has been established. The Hg2+ ions were first bound to the Au NP surface to form gold amalgam, and then the catalytic activity of Au NPs was initiated. This detection method showed the advantages of a fast response time, and high sensitivity and selectivity. The response time and the limit of detection were as low as 2 s and 103 pM, respectively, benefiting from the uniform cavities and the large specific surface area of Fe-TCPP-MOF, which ensure: (1) uniform dispersion of the Au NPs on the surface of the cavity; and (2) a higher chance of interaction of mercury and MB owing to the gathering effect of Fe-TCPP-MOF.

Graphical abstract: Colorimetric detection of Hg(ii) based on the gold amalgam-triggered reductase mimetic activity in aqueous solution by employing AuNP@MOF nanoparticles

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Supplementary files

Article information


Submitted
26 Dec 2019
Accepted
19 Jan 2020
First published
20 Jan 2020

Analyst, 2020, Advance Article
Article type
Paper

Colorimetric detection of Hg(II) based on the gold amalgam-triggered reductase mimetic activity in aqueous solution by employing AuNP@MOF nanoparticles

X. Wang, H. Wang, L. Guo, G. Chen, R. Kong, F. Qu and L. Xia, Analyst, 2020, Advance Article , DOI: 10.1039/C9AN02615K

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