Jump to main content
Jump to site search

Issue 4, 2020
Previous Article Next Article

Colorimetric detection of Hg(ii) based on the gold amalgam-triggered reductase mimetic activity in aqueous solution by employing AuNP@MOF nanoparticles

Author affiliations

Abstract

Although the potential of gold amalgam as a nanoenzyme has been demonstrated, its practical utility has been limited by its low catalytic activity caused by the aggregation of Au nanoparticles (Au NPs). Thus, there is a need to further engineer Au NPs to prevent aggregation and then to achieve higher enzyme activities for the detection of Hg2+ ions. Metal organic frameworks (MOFs), as one kind of promising material, have attracted particular attention due to their unique characteristics of uniform cavities and very high porosity. Herein, a hybrid material of Au nanoparticles and a MOF (AuNP@MOF), constructed by immobilization of Au NPs uniformly on the cavity surface of an iron-5,10,15,20-tetrakis (4-carboxyl)-21H,23H-porphyrin-based MOF (Fe-TCPP-MOF), has been successfully synthesized. Based on Hg2+ ion triggered Au catalysis of methylene blue (MB) reduction, a colorimetric method for highly sensitive and selective detection of Hg2+ ions has been established. The Hg2+ ions were first bound to the Au NP surface to form gold amalgam, and then the catalytic activity of Au NPs was initiated. This detection method showed the advantages of a fast response time, and high sensitivity and selectivity. The response time and the limit of detection were as low as 2 s and 103 pM, respectively, benefiting from the uniform cavities and the large specific surface area of Fe-TCPP-MOF, which ensure: (1) uniform dispersion of the Au NPs on the surface of the cavity; and (2) a higher chance of interaction of mercury and MB owing to the gathering effect of Fe-TCPP-MOF.

Graphical abstract: Colorimetric detection of Hg(ii) based on the gold amalgam-triggered reductase mimetic activity in aqueous solution by employing AuNP@MOF nanoparticles

Back to tab navigation

Supplementary files

Article information


Submitted
26 Dec 2019
Accepted
19 Jan 2020
First published
20 Jan 2020

Analyst, 2020,145, 1362-1367
Article type
Paper

Colorimetric detection of Hg(II) based on the gold amalgam-triggered reductase mimetic activity in aqueous solution by employing AuNP@MOF nanoparticles

X. Wang, H. Wang, L. Guo, G. Chen, R. Kong, F. Qu and L. Xia, Analyst, 2020, 145, 1362
DOI: 10.1039/C9AN02615K

Social activity

Search articles by author

Spotlight

Advertisements