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Issue 10, 2020
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Electrochemical biosensing platforms on the basis of reduced graphene oxide and its composites with Au nanodots

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Abstract

Reduced graphene oxide (rGO) and Au nanodot (AuND, ∼1.5 nm) modified rGO, referred to as AuNDs-rGO, synthesized by a simple photochemical reduction method, are used for electrochemical biosensors. Our experimental results showed that the glucose oxidase (GOX)/rGO/Nafion/glassy carbon electrode (GCE) exhibits a linear range from 0.03 to 6.28 mM and a detection limit of 0.03 mM at a signal-to-noise (S/N) ratio of 3 for the amperometric sensing of glucose, while the GOX/AuNDs-rGO/Nafion/GCE shows a wider linear range from 0.02 to 8.82 mM and a lower detection limit of 0.02 mM. This difference may arise from the high catalytic activity of the AuNDs. Our studies demonstrate that the composites of rGO/Nafion and AuNDs-rGO/Nafion might offer a new class of electrode materials, and provide a promising platform for biosensing applications.

Graphical abstract: Electrochemical biosensing platforms on the basis of reduced graphene oxide and its composites with Au nanodots

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Article information


Submitted
21 Dec 2019
Accepted
20 Mar 2020
First published
20 Mar 2020

Analyst, 2020,145, 3749-3756
Article type
Paper

Electrochemical biosensing platforms on the basis of reduced graphene oxide and its composites with Au nanodots

L. Mei, Q. Zhang, M. Du and Z. Zeng, Analyst, 2020, 145, 3749
DOI: 10.1039/C9AN02592H

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