Facile synthesis of cyclodextrin-metal organic framework decorated with Ketjen Black and platinum nanoparticles and its application for the electrochemical detection of ofloxacin
A facile and novel method was developed to improve the conductivity of a cyclodextrin-metal organic frameworks (CD-MOFs) by modifying it with Ketjen Black (KB) and Pt nanoparticles (PtNPs). The structural morphology and composition of this PtNPs/KB/CD-MOFs nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, mapping, and Raman spectroscopy. The sensor was then evaluated for ability to detect ofloxacin using cyclic voltammetry, and the results showed that the PtNPs/KB/CD-MOFs had high sensitivity, satisfactory stability and good reproducibility. In addition, a great linear range was obtained with a concentration of 0.08-100 µM and a low detection limit of 0.037 µM (S/N = 3). Therefore, the prepared electrochemical sensor could be successfully used to detect ofloxacin in serum.