A robust and efficient aqueous electrochemiluminescence emitter constructed by sulfonate porphyrin-based metal-organic framework and its application in ascorbic acid detection
Robust and strong electrochemiluminescence (ECL) emission of organic emitters in aqueous solution is crucial for expanding their applications in early diagnosis. Herein, Zn-based porphyrin-based metal-organic-framework ((Zn)porphMOF) was facilely obtained by chelating Zn(II)meso-tetra (4-sulfonatophenyl) porphine (Zn-TSPP) with Zn ion, showing substantially enhanced ECL radiation with K2S2O8-coreactants via the “reduction-oxidation” route in aqueous media. Contrast with Zn-TSPP, the ECL intensity of the (Zn)porphMOF displayed 22-time increase in the ECL intensity because of the agglomeration effects. By virtue of the dramatic confinement in the energy and electron transfer of ascorbic acid (AA) in the ECL process, an ultrasensitive biosensor was developed with a wide linear range (3.77 to 26.4 M) and ultra-low detection limit of 0.29 M (3 S/N). This work offers a feasible avenue to harvest the steady and boosting ECL responses of organic molecular in aqueous media, also greatly expanding the MOF application in bioanalysis.