Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments
Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique with sensitivity down to the single molecule level that provides fine molecular fingerprints, allowing for direct identification of target analytes. Extensive theoretical and experimental research, together with continuous development of nanotechnology, has significantly broadened the scope of SERS and made it a hot research field in chemistry, physics, materials, biomedicine, and so on. However, SERS has not been developed into a routine analytical technique, and continuous efforts have been made to address the problems preventing its real-world application. The present minireview focuses on analyzing current and potential strategies to tackle problems and realize the SERS performance necessary for translation to practical applications.
- This article is part of the themed collections: Celebrating a Century of Excellency in Chemistry at Xiamen University, Most popular 2019-2020 review articles and Advances in Optical and Electrochemical Techniques for Biomedical Imaging