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Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium

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Abstract

Isochromenes have been synthesized using palladium-catalyzed C–C and C–O bond forming reactions starting from ortho-bromo tertiary benzylic alcohols and internal acetylenes. Notably, this domino process is feasible by using the green solvent, water. The protocol exhibited a broad substrate scope and afforded various isochromenes.

Graphical abstract: Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium

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Supplementary files

Article information


Submitted
26 Oct 2019
Accepted
15 Dec 2019
First published
02 Jan 2020

This article is Open Access

RSC Adv., 2020,10, 338-349
Article type
Paper

Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium

L. Punia, K. Ramesh and G. Satyanarayana, RSC Adv., 2020, 10, 338
DOI: 10.1039/C9RA08792C

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