Jump to main content
Jump to site search

Issue 98, 2020
Previous Article Next Article

Protein-recruiting synthetic molecules targeting the Golgi surface

Author affiliations

Abstract

Organelle-localizable small-molecule ligands are valuable tools for spatiotemporally controlling protein localization and signaling processes in living cells. Here, we present synthetic ligands that specifically localize to the Golgi surface. The ligands can rapidly recruit their target proteins from the cytoplasm to the Golgi and be applied to manipulate signaling proteins and lipids on the Golgi membrane, offering a new useful chemical tool for the study and control of Golgi/cell functions.

Graphical abstract: Protein-recruiting synthetic molecules targeting the Golgi surface

Back to tab navigation

Supplementary files

Article information


Submitted
16 Oct 2020
Accepted
20 Nov 2020
First published
20 Nov 2020

Chem. Commun., 2020,56, 15422-15425
Article type
Communication

Protein-recruiting synthetic molecules targeting the Golgi surface

S. Sawada, A. Nakamura, T. Yoshii, K. Kuwata, F. Nakatsu and S. Tsukiji, Chem. Commun., 2020, 56, 15422 DOI: 10.1039/D0CC06908F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements