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Issue 72, 2020
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A systematic study on the discrepancy of fluorescence properties between in solutions and in cells: super-bright, environment-insensitive benzocoumarin dyes

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Abstract

The benzocoumarin dyes fluoresce negligibly in aqueous media but very strongly in cells, whereas representative conventional dyes display contrasting behaviour; the distinct emission behaviour of the fluorophores in organic solutions, in aqueous media, and in cell convinces the uniqueness of the cellular environment. The in cellulo superbright benzocoumarins also reveal an environment-insensitive emission behaviour, which is required for the reliable analysis via ratiometric imaging.

Graphical abstract: A systematic study on the discrepancy of fluorescence properties between in solutions and in cells: super-bright, environment-insensitive benzocoumarin dyes

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Article information


Submitted
20 May 2020
Accepted
02 Jul 2020
First published
22 Jul 2020

Chem. Commun., 2020,56, 10556-10559
Article type
Communication

A systematic study on the discrepancy of fluorescence properties between in solutions and in cells: super-bright, environment-insensitive benzocoumarin dyes

Y. J. Reo, Y. W. Jun, S. W. Cho, J. Jeon, H. Roh, S. Singha, M. Dai, S. Sarkar, H. R. Kim, S. Kim, Y. Jin, Y. L. Jung, Y. J. Yang, C. Ban, J. Joo and K. H. Ahn, Chem. Commun., 2020, 56, 10556
DOI: 10.1039/D0CC03586F

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