Jump to main content
Jump to site search


A non-enzymatic glucose sensor with enhanced anti-interference ability based on a MIL-53(NiFe) metal–organic framework

Author affiliations

Abstract

Non-enzymatic glucose sensors are attracting significant attention owing to their low cost, storage convenience and reusability; however, their poor anti-interference caused by their weak selectivity towards glucose limits their practicability. In the present study, a MIL-53(NiFe) metal–organic framework (MOF) was prepared on Ni foam to serve as a self-supported electrode for non-enzymatic glucose detection. Due to the abundant active sites in the MIL-53(NiFe) MOF and its good stability in an alkaline solution, the sensors exhibited a high sensitivity (41.95 mA mM−1 cm−2) and a low detection limit (0.67 μM). Moreover, the molecular sieve effect of the MIL-53(NiFe) MOF led to a remarkable anti-interference ability, even at the interference concentrations of up to 20% glucose, a higher value than that in human serum. In addition, a heat treatment was carried out to remove the residual terephthalic acid in the MOF tunnels, and this promoted the detection linear range to 2–1600 μM. The reusability, reproducibility and long-term stability of the sensors were also studied, and the results implied good practicability of the MIL-53(NiFe) MOF-based sensors. Furthermore, the good practicability of the sensors was verified by testing human serum samples. The results showed the relative standard deviation of 2.73% from the hospital results, and the standard recovery was nearly 100%.

Graphical abstract: A non-enzymatic glucose sensor with enhanced anti-interference ability based on a MIL-53(NiFe) metal–organic framework

Back to tab navigation

Supplementary files

Publication details

The article was received on 27 Aug 2019, accepted on 02 Oct 2019 and first published on 03 Oct 2019


Article type: Paper
DOI: 10.1039/C9TB01832H
J. Mater. Chem. B, 2019, Advance Article

  •   Request permissions

    A non-enzymatic glucose sensor with enhanced anti-interference ability based on a MIL-53(NiFe) metal–organic framework

    L. Zhang, X. Ma, H. Liang, H. Lin and G. Zhao, J. Mater. Chem. B, 2019, Advance Article , DOI: 10.1039/C9TB01832H

Search articles by author

Spotlight

Advertisements