Progress on Electrospun Composite Nanofibers: Composition, Performance and Applications for Tissue Engineering
The discovery of novel method to fabricate optimal scaffold which mimics both mechanical and functional properties resembling the extracellular matrix (ECM) has always been the “holy grail” in tissue engineering. In recent years, electrospinning has been emerging as a attracting material fabricating method and has been widely applied in tissue engineering for the capability of producing non-woven and nanoscale fibers. However, from the perspective of biomimicry, single-component electrospun fiber membranes are difficult to achieve the biomimetic purpose of the multi-component extracellular matrix. Based on electrospinning, various functional components could be efficiently and expediently introduced into the membranes and through the complementation and correlation of the properties of each component, the composite materials with comprehensive and superior properties are obtained while maintaining the primitive merits of each component. In this review, we will provide an overview of the attempts to fabricate electrospinning-based composite tissue engineering material in the past decades, divided into organic additives, inorganic additives and organic-inorganic additives.
- This article is part of the themed collection: Recent Review Articles