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Issue 37, 2019
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Layered double hydroxide nanostructures and nanocomposites for biomedical applications

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Abstract

Layered double hydroxide (LDH) nanostructures and related nanocomposites have attracted significant interest in biomedical applications including cancer therapy, bioimaging and antibacterial treatment. These materials hold great advantages including low cost and facile preparation, convenient drug loading, high drug incorporation capacity, good biocompatibility, efficient intracellular uptake and endosome/lysosome escape, and natural biodegradability in an acidic environment. In this review, we summarize the development of three types of LDH nanostructures including pristine LDH, surface modified LDH, and LDH nanocomposites for a range of biomedical applications. The advantages and disadvantages of LDH nanostructures and insights into the future development are also discussed.

Graphical abstract: Layered double hydroxide nanostructures and nanocomposites for biomedical applications

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Publication details

The article was received on 28 Jun 2019, accepted on 24 Aug 2019 and first published on 29 Aug 2019


Article type: Review Article
DOI: 10.1039/C9TB01312A
J. Mater. Chem. B, 2019,7, 5583-5601
  • Open access: Creative Commons BY license
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    Layered double hydroxide nanostructures and nanocomposites for biomedical applications

    L. Yan, S. Gonca, G. Zhu, W. Zhang and X. Chen, J. Mater. Chem. B, 2019, 7, 5583
    DOI: 10.1039/C9TB01312A

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