Issue 35, 2019

A theranostic saponin nano-assembly based on FRET of an aggregation-induced emission photosensitizer and photon up-conversion nanoparticles

Abstract

A photodynamic aggregation-induced emissive (AIE) fluorophore, characterized by near-infrared (NIR) emission, was created based on a fluorescence resonance energy transfer (FRET) donor of appreciable NIR up-conversion nanoparticles (UCNPs) and acceptor of immense fluorescence emissive AIEgen. Hence, the entrapment of the FRET couple into an amphiphilic saponin-based nanoscaled self-assembly demonstrated appealing theranostic functions in producing immense fluorescence emission and cytotoxic reactive oxygen species (ROS).

Graphical abstract: A theranostic saponin nano-assembly based on FRET of an aggregation-induced emission photosensitizer and photon up-conversion nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
22 Jun 2019
Accepted
12 Aug 2019
First published
13 Aug 2019

J. Mater. Chem. B, 2019,7, 5286-5290

A theranostic saponin nano-assembly based on FRET of an aggregation-induced emission photosensitizer and photon up-conversion nanoparticles

H. Fu, Y. Huang, H. Lu, J. An, De-E. Liu, Y. Zhang, Q. Chen and H. Gao, J. Mater. Chem. B, 2019, 7, 5286 DOI: 10.1039/C9TB01248F

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