Jump to main content
Jump to site search

Issue 30, 2019
Previous Article Next Article

Pivotal role of electrospun nanofibers in microfluidic diagnostic systems – a review

Author affiliations

Abstract

Recently, the usage of electrospinning technology for the fabrication of fine fibers with a good deal of variation in morphology and structure has drawn the attention of many researchers around the world. These fibers have found their way in the many fields of science including medical diagnosis, tissue engineering, drug delivery, replica molding, solar cells, catalysts, energy conversion and storage, physical and chemical sensors and other applications. Among all applications, biosensing with the aim of rapid and sensitive biomarker detection is an area that warrants attention. Electrospun nanofibrous membranes enjoy numerous factors which benefit them to be used as potential candidates in biosensing platforms. Some of these factors include a high surface to volume ratio, analogous scale compared to bioactive molecules and relatively defect-free properties of nanofibers (NFs). In this review, we focused on the recent advances in electrospun nanofibrous membrane-based micro-analytical devices with an application as diagnostic systems. Hence, a study on the electrospun nanofiber usage in lab-on-a-chip and paper-based point-of-care devices, with an opening introduction to biosensors, nanofibers, the electrospinning method, and microfluidics as the principles of the intended subject, is provided. It is anticipated that the given examples in this paper will provide sufficient evidence for the potential of electrospun NFs for being used as a substrate in the commercial fabrication of highly sensitive and selective biosensors.

Graphical abstract: Pivotal role of electrospun nanofibers in microfluidic diagnostic systems – a review

Back to tab navigation

Article information


Submitted
09 Apr 2019
Accepted
25 Jun 2019
First published
01 Jul 2019

J. Mater. Chem. B, 2019,7, 4602-4619
Article type
Review Article

Pivotal role of electrospun nanofibers in microfluidic diagnostic systems – a review

Z. Rezaei and M. Mahmoudifard, J. Mater. Chem. B, 2019, 7, 4602
DOI: 10.1039/C9TB00682F

Social activity

Search articles by author

Spotlight

Advertisements