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A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging

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Abstract

A novel fluorescent sensor CysW-1 was introduced for cysteine detection via the cleavage reaction of two fluorophores. It exhibited advantages including high sensitivity, high selectivity and low toxicity. By optimizing the conditions, a relatively steady and practical white light emitting system was successfully generated. The system was applicable in a wide pH range (7.0–12.0) and a long period (over 12 h). The most attractive point of CysW-1 was its biocompatibility, which ensured the application of the white light emitting system in living cell imaging and further pre-clinical potential.

Graphical abstract: A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging

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Publication details

The article was received on 07 Feb 2019, accepted on 02 Apr 2019 and first published on 06 Apr 2019


Article type: Communication
DOI: 10.1039/C9TB00273A
Citation: J. Mater. Chem. B, 2019, Advance Article

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    A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging

    Y. Yang, Z. Yuan, X. Zhang, J. Xu, P. Lv and H. Zhu, J. Mater. Chem. B, 2019, Advance Article , DOI: 10.1039/C9TB00273A

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