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A hollow microshuttle-shaped capsule covalent organic framework for protein adsorption

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Abstract

Covalent organic frameworks (COFs) are a class of crystalline porous materials utilized in various potential applications. However, the development of hollow-structured COFs with defined morphology is important for their further applications, which is rare. Herein, COF with unique hollow shuttle morphology was prepared by a Schiff condensation reaction between 4-(4-aldehyde phenyl)ethylene (TPE) and tetra-(4-aminophenyl) porphyrin (TAP). A detailed mechanistic investigation reveals that an initial self-assembly followed by a similar inside–out Ostwald ripening process is responsible for the hollow capsule formation. The hollow microshuttle-shaped capsule COF is used for studying hemoglobin adsorption, which shows an uptake of 550.82 mg g−1 of hemoglobin. These studies could foreshadow new avenues for the development of porous materials with defined morphologies for the adsorption of biomolecules.

Graphical abstract: A hollow microshuttle-shaped capsule covalent organic framework for protein adsorption

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Publication details

The article was received on 31 Oct 2018, accepted on 23 Jan 2019 and first published on 25 Jan 2019


Article type: Paper
DOI: 10.1039/C8TB02870B
Citation: J. Mater. Chem. B, 2019, Advance Article

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    A hollow microshuttle-shaped capsule covalent organic framework for protein adsorption

    Z. Lu, Y. Liu, X. Liu, S. Lu, Y. Li, S. Yang, Y. Qin, L. Zheng and H. Zhang, J. Mater. Chem. B, 2019, Advance Article , DOI: 10.1039/C8TB02870B

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