Jump to main content
Jump to site search


Dual-template cascade synthesis of highly multi-branched Au nanoshells with ultrastrong NIR absorption and efficient photothermal therapeutic intervention

Author affiliations

Abstract

With the rapid development of photothermal therapy (PTT) in cancer treatment, it is necessary to obtain effective plasma-responsive tunable photothermal transducing agents. Inspired by the peptide-directed hierarchical mineralized Ag nanocages (Ag NCs), scientists designed a new duel-template cascade preparation method, and novel unique multi-branched gold nanoshells (BGSs) were successfully prepared under mild conditions using green strategy. The length, density and diameter of the branches were tuned, which led to the adjustment of the surface plasma response of the nanostructure. Because of the hierarchical structure and anisotropic surface, an obvious red shift of the local surface plasmon resonance spectrum was observed for the branched Au nanoshells. The excellent photothermal conversion efficiency (70.9%) and photo-induced heating responsive curves proved the superior photothermal conversion performance and photothermal stability of BGSs. The in vitro and in vivo results indicated that the heat generated by the intense NIR absorption of BGSs can selectively destroy cancer cells under laser irradiation. The nanostructures with ultrastrong absorption have promising prospects in tumor therapy.

Graphical abstract: Dual-template cascade synthesis of highly multi-branched Au nanoshells with ultrastrong NIR absorption and efficient photothermal therapeutic intervention

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Oct 2018, accepted on 07 Dec 2018 and first published on 12 Dec 2018


Article type: Paper
DOI: 10.1039/C8TB02753F
Citation: J. Mater. Chem. B, 2019, Advance Article
  •   Request permissions

    Dual-template cascade synthesis of highly multi-branched Au nanoshells with ultrastrong NIR absorption and efficient photothermal therapeutic intervention

    K. Bian, X. Zhang, M. Yang, L. Luo, L. Li, Y. He, C. Cong, X. Li, R. Zhu and D. Gao, J. Mater. Chem. B, 2019, Advance Article , DOI: 10.1039/C8TB02753F

Search articles by author

Spotlight

Advertisements