Jooneon Park, Huiyun Gao, Yunmei Wang, He Hu, Daniel I. Simon and Nicole F. Steinmetz
J. Mater. Chem. B, 2019,7, 1842-1846
DOI:
10.1039/C8TB02276C,
Communication
We integrate a biocompatible plant virus-based nanotechnology (tobacco mosaic virus, TMV) with S100A9-targeting peptides for its application in imaging and diagnosis of atherosclerosis. S100A9-targeted TMV nanoparticles exhibit remarkable specificity to S100A9 and targeting of atherosclerosis lesions in ApoE−/− mice.