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Photoluminescent metal–organic frameworks and their application for sensing biomolecules

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Abstract

Photoluminescence of metal–organic frameworks (MOFs) is sensitive to the structure and concentration of chemical species in the surroundings since MOFs combine the advantages of highly ordered porous structures, varied luminescence origins and diversified host–guest interactions. The diversity and combination flexibility of the organic and inorganic components together with the voids within MOFs offer ample possibilities for tuning their luminescence properties. On the basis of their intrinsic framework structures and biocompatible building blocks, MOFs have stimulated great interest in the area of biosensors. By elaborating on these points, this review will provide up-to-date developments in luminescent MOFs (LMOFs) with emphasis on synthetic approaches and their application in sensing biomolecules. The design outline of LMOFs including functionalization with fluorescent linkers and metal centers and incorporating fluorescent guest molecules within MOFs is presented, and the sensing properties of LMOFs for biomolecules such as DNA/RNA, enzymes/proteins, amino acids, glucose, ascorbic acid, and antibiotics are summarized.

Graphical abstract: Photoluminescent metal–organic frameworks and their application for sensing biomolecules

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Publication details

The article was received on 30 Jun 2019, accepted on 09 Sep 2019 and first published on 10 Sep 2019


Article type: Review Article
DOI: 10.1039/C9TA07022B
J. Mater. Chem. A, 2019, Advance Article

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    Photoluminescent metal–organic frameworks and their application for sensing biomolecules

    J. Dong, D. Zhao, Y. Lu and W. Sun, J. Mater. Chem. A, 2019, Advance Article , DOI: 10.1039/C9TA07022B

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