Jump to main content
Jump to site search


Fabrication of novel MXene (Ti3C2)/polyacrylamide nanocomposite hydrogels with enhanced mechanical and drug release properties

Author affiliations

Abstract

A highly stretchable nanocomposite (NC) hydrogel was fabricated via in situ free radical polymerization of acrylamide. In particular, an exfoliated two-dimensional MXene (Ti3C2) nanosheet was utilized as a crosslinker instead of traditional organic crosslinkers. The exfoliated Ti3C2 nanosheets were confirmed by atomic force microscopy (AFM) and dynamic light scattering (DLS) measurements. Compared with traditional organic crosslinked N,N-methylene bisacrylamide (BIS)/polyacrylamide (PAM) hydrogels (fracture strength of 32.0 kPa and elongation of 109.6%), the synthesized Ti3C2/PAM NC hydrogels exhibited greatly improved mechanical properties with fracture strengths of 66.5 to 102.7 kPa, compressive strengths of 400.6 to 819.4 kPa and elongations at break of 2158.6% to 3047.5% as the Ti3C2 content increases from 0.0145% to 0.0436%. The enhanced mechanical performances can be attributed to the honeycomb-like fine structure with uniform pores as well as more flexible polymer chains in NC hydrogel networks. When loaded with drugs, Ti3C2/PAM NC hydrogels exhibited good sustained-release performance, higher drug loading amounts (97.5–127.7 mg g−1) and higher percentage releases (62.1–81.4%), greatly superior to those of the BIS/PAM hydrogel (46.4 mg g−1, 45.0%). Our work reveals the application of MXene materials in the fabrication of NC hydrogels with enhanced mechanical and drug release behaviors.

Graphical abstract: Fabrication of novel MXene (Ti3C2)/polyacrylamide nanocomposite hydrogels with enhanced mechanical and drug release properties

Back to tab navigation

Supplementary files

Publication details

The article was received on 03 Oct 2019, accepted on 10 Nov 2019 and first published on 13 Nov 2019


Article type: Paper
DOI: 10.1039/C9SM01985E
Soft Matter, 2020, Advance Article

  •   Request permissions

    Fabrication of novel MXene (Ti3C2)/polyacrylamide nanocomposite hydrogels with enhanced mechanical and drug release properties

    P. Zhang, X. Yang, P. Li, Y. Zhao and Q. J. Niu, Soft Matter, 2020, Advance Article , DOI: 10.1039/C9SM01985E

Search articles by author

Spotlight

Advertisements