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The influence of device handles in single-molecule experiments

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Abstract

We deduce a fully analytical model to predict the artifacts of the device handles in single molecule force spectroscopy experiments. As we show, neglecting the handle stiffness can lead to crucial overestimation or underestimation of the stability properties and unfolding thresholds of multistable molecules.

Graphical abstract: The influence of device handles in single-molecule experiments

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Publication details

The article was received on 08 Jul 2019, accepted on 28 Sep 2019 and first published on 02 Oct 2019


Article type: Paper
DOI: 10.1039/C9SM01376H
Soft Matter, 2019, Advance Article

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    The influence of device handles in single-molecule experiments

    L. Bellino, G. Florio and G. Puglisi, Soft Matter, 2019, Advance Article , DOI: 10.1039/C9SM01376H

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