Jump to main content
Jump to site search

Issue 31, 2019
Previous Article Next Article

Using cavitation rheology to understand dipeptide-based low molecular weight gels

Author affiliations

Abstract

The study of dipeptide-based hydrogels has been the focus of significant effort recently due to their potential for use in a variety of biomedical and biotechnological applications. It is essential to study the mechanical properties in order to fully characterise and understand this type of soft materials. In terms of mechanical properties, the linear elastic modulus is normally measured using traditional shear rheometry. This technique requires millilitre sample volumes, which can be difficult when only small amounts of gel are available, and can present difficulties when loading the sample into the machine. Here, we describe the use of cavitation rheology, an easy and efficient technique, to characterise the linear elastic modulus of a range of hydrogels. Unlike traditional shear rheometry, this technique can be used on hydrogels in their native environment, and small sample volumes are required. We describe our set-up and show how it can be used to probe and understand different types of gels. Gels can be formed by different triggers from the same gelator and this leads to different microstructures. We show that the data from the cavitational rheometer correlates with the underlying microstructure in the gels, which allows a greater degree of understanding of the gels than can be obtained from the bulk measurements.

Graphical abstract: Using cavitation rheology to understand dipeptide-based low molecular weight gels

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 May 2019, accepted on 24 Jun 2019 and first published on 24 Jun 2019


Article type: Paper
DOI: 10.1039/C9SM01023H
Soft Matter, 2019,15, 6340-6347
  • Open access: Creative Commons BY license
  •   Request permissions

    Using cavitation rheology to understand dipeptide-based low molecular weight gels

    A. M. Fuentes-Caparrós, B. Dietrich, L. Thomson, C. Chauveau and D. J. Adams, Soft Matter, 2019, 15, 6340
    DOI: 10.1039/C9SM01023H

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements