Jump to main content
Jump to site search


pH-Induced reorientation of cytochrome c on silica nanoparticles

Author affiliations

Abstract

The orientation of cytochrome c molecules at the surface of silica nanoparticles was studied in a wide pH range by combining small-angle neutron scattering, adsorption measurements, and molecular dynamics simulations. The results indicate a reorientation of the ellipsoidal protein from head-on to side-on as the pH is increased. This is attributed to changes in the surface charge distribution of both the protein and the nanoparticles.

Graphical abstract: pH-Induced reorientation of cytochrome c on silica nanoparticles

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Sep 2018, accepted on 16 Nov 2018 and first published on 16 Nov 2018


Article type: Communication
DOI: 10.1039/C8SM01909F
Citation: Soft Matter, 2019, Advance Article
  •   Request permissions

    pH-Induced reorientation of cytochrome c on silica nanoparticles

    J. Meissner, Y. Wu, J. Jestin, W. A. Shelton, G. H. Findenegg and B. Bharti, Soft Matter, 2019, Advance Article , DOI: 10.1039/C8SM01909F

Search articles by author

Spotlight

Advertisements