Issue 33, 2019

Using chirality to influence supramolecular gelation


Most low molecular weight gelators are chiral, with racemic mixtures often unable to form gels. Here, we show an example where all enantiomers, diastereomers and racemates of a single functionalized dipeptide can form gels. At high pH, different self-assembled aggregates are formed and these directly template the structures formed in the gel. Hence, solutions and gels with different properties can be accessed simply by varying the chirality. This opens up new design rules for the field.

Graphical abstract: Using chirality to influence supramolecular gelation

Supplementary files

Article information

Article type
Edge Article
08 May 2019
03 Jul 2019
First published
03 Jul 2019
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2019,10, 7801-7806

Using chirality to influence supramolecular gelation

K. McAulay, B. Dietrich, H. Su, M. T. Scott, S. Rogers, Y. K. Al-Hilaly, H. Cui, L. C. Serpell, Annela M. Seddon, E. R. Draper and D. J. Adams, Chem. Sci., 2019, 10, 7801 DOI: 10.1039/C9SC02239B

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