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Issue 11, 2019
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Biocatalysis explained: from pharmaceutical to bulk chemical production

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Abstract

Biocatalysis is one of the most promising technologies for the sustainable synthesis of molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to the ton scale, biocatalysis is employed with success. This is underpinned by the fact that the global enzyme market is predicted to increase from $7 billion to $10 billion by 2024. This review concentrates on showing the strong benefits that biocatalysis and the use of enzymes can provide to synthetic chemistry. Several examples of successful implementations of enzymes are discussed highlighting not only high-value pharmaceutical processes but also low-cost bulk products. Thus, biocatalytic methods make the chemistry more environmentally friendly and product specific.

Graphical abstract: Biocatalysis explained: from pharmaceutical to bulk chemical production

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Publication details

The article was received on 26 Jul 2019, accepted on 10 Sep 2019 and first published on 11 Sep 2019


Article type: Review Article
DOI: 10.1039/C9RE00301K
React. Chem. Eng., 2019,4, 1878-1894
  • Open access: Creative Commons BY license
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    Biocatalysis explained: from pharmaceutical to bulk chemical production

    E. M. M. Abdelraheem, H. Busch, U. Hanefeld and F. Tonin, React. Chem. Eng., 2019, 4, 1878
    DOI: 10.1039/C9RE00301K

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