Jump to main content
Jump to site search


Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki–Miyaura coupling reactions under flow conditions

Author affiliations

Abstract

An immobilized triphenylphosphine scaffold was prepared by precipitation polymerization and functionalized to afford a cost-effective source of solid-supported tetrakis(triphenylphosphine)palladium(0). The catalyst was characterised and used to perform biphasic Suzuki–Miyaura cross-coupling reactions using a packed-bed reactor under flow conditions. The approach afforded comparable yields to those obtained under batch conditions with a single pass through the packed-bed reactor (1 h vs. 18 h). The use of a recycling system was investigated on a model reaction and found to afford close to quantitative conversion within 3 hours.

Graphical abstract: Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki–Miyaura coupling reactions under flow conditions

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Oct 2018, accepted on 03 Dec 2018 and first published on 03 Dec 2018


Article type: Paper
DOI: 10.1039/C8RE00235E
Citation: React. Chem. Eng., 2019, Advance Article
  •   Request permissions

    Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki–Miyaura coupling reactions under flow conditions

    G. V. Ramaotsoa, I. Strydom, J. Panayides and D. Riley, React. Chem. Eng., 2019, Advance Article , DOI: 10.1039/C8RE00235E

Search articles by author

Spotlight

Advertisements