Jump to main content
Jump to site search

Issue 2, 2019
Previous Article Next Article

Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki–Miyaura coupling reactions under flow conditions

Author affiliations

Abstract

An immobilized triphenylphosphine scaffold was prepared by precipitation polymerization and functionalized to afford a cost-effective source of solid-supported tetrakis(triphenylphosphine)palladium(0). The catalyst was characterised and used to perform biphasic Suzuki–Miyaura cross-coupling reactions using a packed-bed reactor under flow conditions. The approach afforded comparable yields to those obtained under batch conditions with a single pass through the packed-bed reactor (1 h vs. 18 h). The use of a recycling system was investigated on a model reaction and found to afford close to quantitative conversion within 3 hours.

Graphical abstract: Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki–Miyaura coupling reactions under flow conditions

Back to tab navigation

Supplementary files

Article information


Submitted
02 Oct 2018
Accepted
03 Dec 2018
First published
03 Dec 2018

React. Chem. Eng., 2019,4, 372-382
Article type
Paper

Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki–Miyaura coupling reactions under flow conditions

G. V. Ramaotsoa, I. Strydom, J. Panayides and D. Riley, React. Chem. Eng., 2019, 4, 372
DOI: 10.1039/C8RE00235E

Social activity

Search articles by author

Spotlight

Advertisements