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Issue 34, 2019, Issue in Progress
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Laser-treated glass platform for rapid wicking-driven transport and particle separation in bio microfluidics

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Abstract

In this work, we present a laser-based fabrication technique for direct patterning of micro-channels consisting of interconnected micro-cracks on soda-lime glass. Using a CO2 laser to deposit energy at a linear rate of 18.75 to 93.75 mJ mm−1, we were able to manipulate the micro-crack formation, while enabling rapid manufacturing and scalable production of cracked-glass microfluidic patterns on glass. At the higher end of the energy deposition rate (93.75 mJ mm−1), the laser fabricated microfluidic channels (1 mm wide and 20 mm long) had extremely fast wicking speeds (24.2 mm s−1, ×10 faster than filter paper) as a result of significant capillary action and laser-induced surface hydrophilization. At the lower end (18.75 mJ mm−1), 3–4 μm wide micro-cracked crevices resulted in an increased mesh/sieve density, hence, more efficiently filtering particle-laden liquid samples. The reproducibility tests revealed an averaged wicking speed of 10.6 ± 1.5 mm s−1 measured over 21 samples fabricated under similar conditions, similar to that of filter paper (∼85%). The micro-cracked channels exhibited a stable shelf life of at least 82 days with a wicking speed within 10–13 mm s−1.

Graphical abstract: Laser-treated glass platform for rapid wicking-driven transport and particle separation in bio microfluidics

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Article information


Submitted
08 May 2019
Accepted
11 Jun 2019
First published
21 Jun 2019

This article is Open Access

RSC Adv., 2019,9, 19531-19538
Article type
Paper

Laser-treated glass platform for rapid wicking-driven transport and particle separation in bio microfluidics

H. Jiang, M. Ochoa, R. Rahimi, W. Yu and B. Ziaie, RSC Adv., 2019, 9, 19531
DOI: 10.1039/C9RA03448J

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