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Issue 20, 2019, Issue in Progress
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Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals

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Abstract

Cerium oxide nanoparticles (CeNPs) have been shown to exhibit antioxidant capabilities, but their efficiency in scavenging reactive oxygen species (ROS) and the underlying mechanisms are not yet well understood. In this study, cerium dioxide nanoparticles (CeNPs) and nanorods (CeNRs) were found to exhibit much stronger scavenging activity than ·OH generation in phosphate buffered saline (PBS) and surrogate lung fluid (SLF). The larger surface area and higher defect density of CeNRs may lead to higher ·OH scavenging activity than for CeNPs. These insights are important to understand the redox activity of cerium nanomaterials and provide clues to the role of CeNPs in biological and environmental processes.

Graphical abstract: Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals

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Supplementary files

Article information


Submitted
24 Jan 2019
Accepted
04 Apr 2019
First published
09 Apr 2019

This article is Open Access

RSC Adv., 2019,9, 11077-11081
Article type
Paper

Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals

A. Filippi, F. Liu, J. Wilson, S. Lelieveld, K. Korschelt, T. Wang, Y. Wang, T. Reich, U. Pöschl, W. Tremel and H. Tong, RSC Adv., 2019, 9, 11077
DOI: 10.1039/C9RA00642G

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    [Original citation] - Published by The Royal Society of Chemistry.

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