Jump to main content
Jump to site search

Issue 22, 2019, Issue in Progress

The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

Author affiliations

Abstract

The mechanical properties of poly(vinyl alcohol) (PVA)-based scaffolds were successfully improved. The improvements in mechanical properties correlated with the amount of Kraft lignin in PVA matrices. The critical property for any scaffold is its capacity to allow cells to ingrow and survive within its internal structure. The ingrowth of cells was tested using bioreactors creating simulated in vivo conditions. In the context of all the mentioned parameters, the most advantageous properties were exhibited by the scaffold containing 99 wt% PVA and 1 wt% Kraft lignin. The composites with 1 wt% Kraft lignin exhibited sufficient mechanical stability, a lack of cytotoxicity, and mainly the ability to allow the ingrowth of cells into the scaffold in a rotation bioreactor.

Graphical abstract: The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

Article information


Submitted
27 Nov 2018
Accepted
13 Apr 2019
First published
23 Apr 2019

This article is Open Access

RSC Adv., 2019,9, 12346-12353
Article type
Paper

The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

P. Rejmontová, A. Kovalcik, P. Humpolíček, Z. Capáková, E. Wrzecionko and P. Sáha, RSC Adv., 2019, 9, 12346 DOI: 10.1039/C8RA09757G

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements