Jump to main content
Jump to site search


Access to chiral cyano-containing five-membered rings through enantioconvergent rhodium-catalyzed cascade cyclization of a diastereoisomeric E/Z mixture of 1,6-enynes

Author affiliations

Abstract

In contrast to the intermolecular rhodium-catalyzed asymmetric 1,4-addition of organometallic reagents to activated alkenes, the asymmetric arylative cyclization of diastereoisomeric E/Z mixture of 1,6-enynes afforded only one major enantiomer.

Graphical abstract: Access to chiral cyano-containing five-membered rings through enantioconvergent rhodium-catalyzed cascade cyclization of a diastereoisomeric E/Z mixture of 1,6-enynes

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Oct 2019, accepted on 01 Nov 2019 and first published on 04 Nov 2019


Article type: Research Article
DOI: 10.1039/C9QO01264H
Org. Chem. Front., 2019, Advance Article

  •   Request permissions

    Access to chiral cyano-containing five-membered rings through enantioconvergent rhodium-catalyzed cascade cyclization of a diastereoisomeric E/Z mixture of 1,6-enynes

    A. Selmani and S. Darses, Org. Chem. Front., 2019, Advance Article , DOI: 10.1039/C9QO01264H

Search articles by author

Spotlight

Advertisements