Jump to main content
Jump to site search


Pd-Catalyzed intramolecular C–H activation and C–S formation to synthesize pyrazolo[5,1-b]benzothiazoles without an additional oxidant

Author affiliations

Abstract

Herein, an efficient synthesis of pyrazolo[5,1-b]benzothiazole scaffold via Pd-catalyzed intramolecular C–H activation and C–S formation was reported. By starting from easily available 1-phenyl-1H-pyrazole-5-thiol compounds, a series of substituted pyrazolo[5,1-b]benzothiazoles were obtained with moderate to good yields. Interestingly, this reaction didn't need any additional oxidant and the reaction conditions were also suitable for the synthesis of imidazo[2,1-b]benzothiazole derivatives.

Graphical abstract: Pd-Catalyzed intramolecular C–H activation and C–S formation to synthesize pyrazolo[5,1-b]benzothiazoles without an additional oxidant

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Apr 2019, accepted on 26 Jul 2019 and first published on 30 Jul 2019


Article type: Research Article
DOI: 10.1039/C9QO00484J
Org. Chem. Front., 2019, Advance Article

  •   Request permissions

    Pd-Catalyzed intramolecular C–H activation and C–S formation to synthesize pyrazolo[5,1-b]benzothiazoles without an additional oxidant

    Y. Peng, Q. He, X. Zhang and C. Yang, Org. Chem. Front., 2019, Advance Article , DOI: 10.1039/C9QO00484J

Search articles by author

Spotlight

Advertisements