Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.



Copper-catalyzed highly diastereoselective cross-dehydrogenative coupling between 8-hydroxyisochromanes and 1,3-dicarbonyl compounds

Author affiliations

Abstract

Herein, a novel copper-catalyzed highly diastereoselective cross-dehydrogenative coupling reaction is reported. A broad range of 1,3-dicarbonyl compounds and 8-hydroxyisochromanes are applicable to this methodology, affording tricyclic chromane products in moderate to high yields with continuous stereocenters identical to natural penicitrinols.

Graphical abstract: Copper-catalyzed highly diastereoselective cross-dehydrogenative coupling between 8-hydroxyisochromanes and 1,3-dicarbonyl compounds

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Mar 2019, accepted on 05 May 2019 and first published on 08 May 2019


Article type: Research Article
DOI: 10.1039/C9QO00353C
Org. Chem. Front., 2019, Advance Article

  •   Request permissions

    Copper-catalyzed highly diastereoselective cross-dehydrogenative coupling between 8-hydroxyisochromanes and 1,3-dicarbonyl compounds

    Z. Zhang, Y. Tu, X. Zhang, F. Zhang and S. Wang, Org. Chem. Front., 2019, Advance Article , DOI: 10.1039/C9QO00353C

Search articles by author

Spotlight

Advertisements