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First synthesis of orthogonally 1,7-diprotected cyclens

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Abstract

The first examples of 1,7-orthogonally diprotected cyclen (1,4,7,10-tetraazacyclododecane) derivatives have been prepared through a straightforward and convenient synthetic strategy. These compounds represent useful starting materials for the preparation of several functionalised macrocyclic chelating agents.

Graphical abstract: First synthesis of orthogonally 1,7-diprotected cyclens

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Publication details

The article was received on 01 Feb 2019, accepted on 20 Mar 2019 and first published on 20 Mar 2019


Article type: Research Article
DOI: 10.1039/C9QO00184K
Citation: Org. Chem. Front., 2019, Advance Article

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    First synthesis of orthogonally 1,7-diprotected cyclens

    F. Travagin, L. Lattuada and G. B. Giovenzana, Org. Chem. Front., 2019, Advance Article , DOI: 10.1039/C9QO00184K

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