Jump to main content
Jump to site search


Cytorhizophins A and B, benzophenone-hemiterpene adducts from the endophytic fungus Cytospora rhizophorae

Author affiliations

Abstract

A pair of novel enantiomeric benzophenone-hemiterpene adducts, (+)-cytorhizophin A (1a) and (−)-cytorhizophin A (1b) as well as cytorhizophin B (2), all of them featuring an unprecedented 6/7/6/7 tetracyclic fused ring system, together with their biosynthetically related precursor cytorhizophin C (3) were isolated from Cytospora rhizophorae A761. Their structures were fully characterized on the basis of extensive spectroscopic analysis, with the absolute configurations of 1 determined by X-ray diffraction and electronic circular dichroism (ECD) calculations. Moreover, compounds 1–3 were evaluated for in vitro antimicrobial activity.

Graphical abstract: Cytorhizophins A and B, benzophenone-hemiterpene adducts from the endophytic fungus Cytospora rhizophorae

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Dec 2018, accepted on 14 Jan 2019 and first published on 15 Jan 2019


Article type: Research Article
DOI: 10.1039/C8QO01306C
Citation: Org. Chem. Front., 2019, Advance Article

  •   Request permissions

    Cytorhizophins A and B, benzophenone-hemiterpene adducts from the endophytic fungus Cytospora rhizophorae

    H. Liu, H. Tan, W. Wang, W. Zhang, Y. Chen, S. Li, Z. Liu, H. Li and W. Zhang, Org. Chem. Front., 2019, Advance Article , DOI: 10.1039/C8QO01306C

Search articles by author

Spotlight

Advertisements