Jump to main content
Jump to site search

Issue 4, 2019
Previous Article Next Article

Water-soluble Re6-clusters with aromatic phosphine ligands – from synthesis to potential biomedical applications

Author affiliations

Abstract

The development of water-soluble hexanuclear cluster complexes of low toxicity is a promising task due to their potential biomedical applications such as bioimaging and photodynamic therapy. Herein, we present the syntheses of two new water-soluble hexarhenium cluster complexes with terminal amphiphilic phosphine ligands, and delineate their photoluminescence and X-ray excited optical luminescence (XEOL) properties. These cluster complexes, namely [{Re6Q8}(PPh2CH2CH2COO)6]4− (Q = S (1); Se, (2)), have the least cytotoxicity among all the tested hexanuclear metal-clusters, are capable of penetrating into cells and exhibit moderate photodynamic toxicity toward Hep-2 cells.

Graphical abstract: Water-soluble Re6-clusters with aromatic phosphine ligands – from synthesis to potential biomedical applications

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Nov 2018, accepted on 09 Jan 2019 and first published on 10 Jan 2019


Article type: Research Article
DOI: 10.1039/C8QI01216D
Citation: Inorg. Chem. Front., 2019,6, 882-892

  •   Request permissions

    Water-soluble Re6-clusters with aromatic phosphine ligands – from synthesis to potential biomedical applications

    A. A. Ivanov, D. I. Konovalov, T. N. Pozmogova, A. O. Solovieva, A. R. Melnikov, K. A. Brylev, N. V. Kuratieva, V. V. Yanshole, K. Kirakci, K. Lang, S. N. Cheltygmasheva, N. Kitamura, L. V. Shestopalova, Y. V. Mironov and M. A. Shestopalov, Inorg. Chem. Front., 2019, 6, 882
    DOI: 10.1039/C8QI01216D

Search articles by author

Spotlight

Advertisements