Jump to main content
Jump to site search

Issue 26, 2019
Previous Article Next Article

Versatile functionalization of polymer nanoparticles with carbonate groups via hydroxyurethane linkages

Author affiliations

Abstract

Synthesis of polymer nanoparticles bearing pendant cyclic carbonate moieties is carried out to explore their potential as versatile supports for biomedical applications and catalysis. Nanoparticles are produced by copolymerizing glycerol carbonate methacrylate with methyl methacrylate by the miniemulsion process. The ability of the nanoparticles to serve as carriers for biomolecules was studied by reacting them with various amines, amino acids, and proteins. The functionalized nanoparticles are systematically analyzed by Fourier transform infrared spectroscopy, solid state (SS) NMR spectroscopy, and X-ray photoelectron spectroscopy. Model studies are performed to investigate the reactivity of amino acids and albumin with the pendant carbonate groups. Functionalization of the nanoparticles with dopamine led to surface coverage with catechol groups as efficient heterogeneous hydrogen bond donors for the cycloaddition of CO2 to epoxides under atmospheric pressure.

Graphical abstract: Versatile functionalization of polymer nanoparticles with carbonate groups via hydroxyurethane linkages

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Apr 2019, accepted on 29 May 2019 and first published on 30 May 2019


Article type: Paper
DOI: 10.1039/C9PY00597H
Polym. Chem., 2019,10, 3571-3584

  •   Request permissions

    Versatile functionalization of polymer nanoparticles with carbonate groups via hydroxyurethane linkages

    N. Yadav, F. Seidi, S. Del Gobbo, V. D'Elia and D. Crespy, Polym. Chem., 2019, 10, 3571
    DOI: 10.1039/C9PY00597H

Search articles by author

Spotlight

Advertisements