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Cationic polycarbonates via ring-opening polymerization: design, synthesis, and applications

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Abstract

Cationic polycarbonates are a class of very important polymers owing to their positively charged moieties and biodegradability. The positively charged moieties in cationic polycarbonates are able to combine anionic compounds such as nucleic acids and proteins to form the polyplexes. The biodegradability of cationic polycarbonates can reduce their toxicity. Here we summarized the reports on cationic polycarbonates via ring-opening polymerization from design and synthesis to applications. The synthetic methods of cationic polycarbonates mainly include ring-opening polymerization of cyclic carbonates containing amino groups and amination of functional polycarbonates. Cationic polycarbonates have been widely applied in biomedical fields such as drug release, gene delivery, and antimicrobial polymers.

Graphical abstract: Cationic polycarbonates via ring-opening polymerization: design, synthesis, and applications

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Publication details

The article was received on 20 Sep 2018, accepted on 03 Nov 2018 and first published on 12 Nov 2018


Article type: Review Article
DOI: 10.1039/C8PY01365A
Citation: Polym. Chem., 2019, Advance Article
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    Cationic polycarbonates via ring-opening polymerization: design, synthesis, and applications

    Y. Dai and X. Zhang, Polym. Chem., 2019, Advance Article , DOI: 10.1039/C8PY01365A

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