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Issue 40, 2019
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Iodine-mediated aminosulfonylation of alkenyl sulfonamides with sulfonyl hydrazides: synthesis of sulfonylmethyl piperidines, pyrrolidines and pyrazolines

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Abstract

An aminosulfonylation of alkenyl sulfonamides was reported. Using iodine as the catalyst, TBHP as the oxidant, and sulfonyl hydrazides as the sulfonyl radical sources, a variety of sulfonylmethyl piperidines, pyrrolidines and pyrazolines were obtained in moderate to excellent yields.

Graphical abstract: Iodine-mediated aminosulfonylation of alkenyl sulfonamides with sulfonyl hydrazides: synthesis of sulfonylmethyl piperidines, pyrrolidines and pyrazolines

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Publication details

The article was received on 22 Aug 2019, accepted on 27 Sep 2019 and first published on 27 Sep 2019


Article type: Paper
DOI: 10.1039/C9OB01847F
Org. Biomol. Chem., 2019,17, 9026-9038

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    Iodine-mediated aminosulfonylation of alkenyl sulfonamides with sulfonyl hydrazides: synthesis of sulfonylmethyl piperidines, pyrrolidines and pyrazolines

    Z. Xu, W. Wang, L. Zheng, L. Li, L. Duan and Y. Li, Org. Biomol. Chem., 2019, 17, 9026
    DOI: 10.1039/C9OB01847F

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