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Issue 39, 2019
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Recognition of mixed-sequence DNA targets using spermine-modified Invader probes

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Abstract

Double-stranded oligodeoxyribonucleotides with +1 interstrand zipper arrangements of 2′-O-(pyren-1-yl)methyl-RNA monomers are additionally activated for highly specific recognition of mixed-sequence DNA targets upon incorporation of non-nucleotidic spermine bulges.

Graphical abstract: Recognition of mixed-sequence DNA targets using spermine-modified Invader probes

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Publication details

The article was received on 31 Jul 2019, accepted on 16 Aug 2019 and first published on 19 Aug 2019


Article type: Communication
DOI: 10.1039/C9OB01686D
Org. Biomol. Chem., 2019,17, 8795-8799

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    Recognition of mixed-sequence DNA targets using spermine-modified Invader probes

    S. P. Adhikari, R. G. Emehiser, S. Karmakar and P. J. Hrdlicka, Org. Biomol. Chem., 2019, 17, 8795
    DOI: 10.1039/C9OB01686D

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