Issue 36, 2019

Recent advances in the synthesis of carbazoles from indoles

Abstract

Carbazoles are privileged nitrogen heterocycles that are present in a wide range of natural products, pharmaceuticals, and functional materials. Due to their wide application, various synthetic strategies are available in the literature using substituted amines or indoles as a substrate. Thus, this review comprehensively highlights the (2015–2019) article that focuses on the synthesis of carbazoles derived from an indole-template through transition-metal catalyzed C–H functionalization, metal-free cyclization, three-component reaction, and electrophilic iodocyclizations. The synthetic strategies described in this review provided diversely substituted carbazoles and few of them have profound pharmacological activity.

Graphical abstract: Recent advances in the synthesis of carbazoles from indoles

Article information

Article type
Review Article
Submitted
19 Jun 2019
Accepted
29 Aug 2019
First published
29 Aug 2019

Org. Biomol. Chem., 2019,17, 8330-8342

Recent advances in the synthesis of carbazoles from indoles

T. Aggarwal, Sushmita and A. K. Verma, Org. Biomol. Chem., 2019, 17, 8330 DOI: 10.1039/C9OB01381D

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