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Issue 36, 2019
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Recent advances in the synthesis of carbazoles from indoles

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Abstract

Carbazoles are privileged nitrogen heterocycles that are present in a wide range of natural products, pharmaceuticals, and functional materials. Due to their wide application, various synthetic strategies are available in the literature using substituted amines or indoles as a substrate. Thus, this review comprehensively highlights the (2015–2019) article that focuses on the synthesis of carbazoles derived from an indole-template through transition-metal catalyzed C–H functionalization, metal-free cyclization, three-component reaction, and electrophilic iodocyclizations. The synthetic strategies described in this review provided diversely substituted carbazoles and few of them have profound pharmacological activity.

Graphical abstract: Recent advances in the synthesis of carbazoles from indoles

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Article information


Submitted
19 Jun 2019
Accepted
29 Aug 2019
First published
29 Aug 2019

Org. Biomol. Chem., 2019,17, 8330-8342
Article type
Review Article

Recent advances in the synthesis of carbazoles from indoles

T. Aggarwal, Sushmita and A. K. Verma, Org. Biomol. Chem., 2019, 17, 8330
DOI: 10.1039/C9OB01381D

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