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o-Hydroxycinnamate for sequential photouncaging of two different functional groups and its application in releasing cosmeceuticals

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Abstract

We demonstrated a new approach for the sequential photouncaging of two different functional groups from o-hydroxycinnamate. The second caged molecule initially remains in the locked state and is released only after attaining its unlocked state upon in situ generation of the second phototrigger, i.e., coumarin, thereby leading to the sequential release of alcohol and carboxylic acid. We have utilised the above strategy for the controlled release of cosmeceutical agents.

Graphical abstract: o-Hydroxycinnamate for sequential photouncaging of two different functional groups and its application in releasing cosmeceuticals

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Publication details

The article was received on 16 May 2019, accepted on 01 Aug 2019 and first published on 01 Aug 2019


Article type: Communication
DOI: 10.1039/C9OB01148J
Org. Biomol. Chem., 2019, Advance Article

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    o-Hydroxycinnamate for sequential photouncaging of two different functional groups and its application in releasing cosmeceuticals

    A. Paul, M. Bera, P. Gupta and N. D. P. Singh, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C9OB01148J

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