Palladium-Catalyzed Carbonylative Synthesis of Substituted Cyclopentenones from Aryl Iodides and Internal Alkynes
In this communcation, a palladium-catalyzed carbonylative synthesis of substituted cyclopentenones has been developed. With aryl iodides and internal alkynes as the substrates, via domino process consisted by formal Pauson-Khand reaction, good yields of the desired products were obtained. Interestingly, formic acid has been used both as hydrogen and carbon monoxide sources in this system.
- This article is part of the themed collection: Synthetic methodology in OBC