Triazole Functionalized Acyclic Cucurbit[n]uril-Type Receptors: Host•Guest Recognition Properties
We report the synthesis of three new triazole functionalized acyclic CB[n]-type receptors (2 – 4) by click chemistry. The compounds have good solubility in water (≥ 8 mM) and do not undergo strong self-association (Ks ≤ 903 M-1). We measured the binding constants of 2 – 4 toward guests 9 – 24 and compared the results to those obtained for the prototypical acyclic CB[n]-type receptor 1. The x-ray crystal structure of 4 is also described.
- This article is part of the themed collection: Supramolecular chemistry in OBC