A facile copper(i)-catalyzed homo-coupling of indanone derivatives using diaziridinone under mild conditions

Abstract

A novel and efficient Cu(I)-catalyzed homo-coupling of indanone derivatives using diaziridinone as an oxidant is described. A variety of 1,4-dicarbonyl compounds bearing two adjacent quaternary stereocenters were obtained in high yields with high diastereoselectivities via a base-free and operationally simple process under mild reaction conditions.