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Issue 27, 2019
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Introduction to chemical warfare agents, relevant simulants and modern neutralisation methods

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Abstract

Despite international prohibition, some ill-intentioned states and organisations have shown their will and capacity to run chemical weapon programs, and the number of incidents involving chemical warfare agents (CWA) has significantly increased in recent years. Herein, we aimed to offer a clear overview of chemical warfare agents to organic chemists not specialized in this field by (1) introducing the main CWAs and their relevant simulants legally usable in academic laboratories and (2) presenting a selection of recent and soft neutralisation methods, such as organocatalysis and continuous flow, and materials such as metal–organic frameworks and polyoxometalates. These modern approaches offer potential future alternatives to “heavy” decontamination methods.

Graphical abstract: Introduction to chemical warfare agents, relevant simulants and modern neutralisation methods

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Article information


Submitted
07 Apr 2019
Accepted
05 Jun 2019
First published
05 Jun 2019

Org. Biomol. Chem., 2019,17, 6528-6537
Article type
Review Article

Introduction to chemical warfare agents, relevant simulants and modern neutralisation methods

B. Picard, I. Chataigner, J. Maddaluno and J. Legros, Org. Biomol. Chem., 2019, 17, 6528
DOI: 10.1039/C9OB00802K

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