Bo Cao, Yin Wei and Min Shi
Org. Biomol. Chem., 2019,17, 3737-3740
DOI:
10.1039/C9OB00585D,
Communication
A cascade cyclization of para-quinamines and 2-furanylmethanol has been achieved, affording a series of functionalized hydrobenzo[c,d]indoles in moderate to good yields and excellent diastereoselectivities under mild conditions. This reaction was first initiated by the Mitsunobu reaction and then followed by the [4 + 2] Diels–Alder reaction to furnish the important indole-fused heterocyclic derivatives.
![Graphical abstract: Mitsunobu-initiated cascade cyclization of p-quinamines and 2-furanylmethanols: highly regio- and diastereoselective synthesis of functionalized hydrobenzo[c,d]indoles](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C9OB00585D "Graphical abstract")
